Women told HRT does not lead to early death

Women told HRT does not lead to early death

Women told HRT does not lead to early death

That research was halted early when more breast cancer, heart attacks and strokes occurred in women on combined pills than in dummy pill users.

The door may be opening again for menopausal women suffering from hot flashes and night sweats to receive some relief from a source once thought too unsafe to consider, researchers say.

The clinical trial "provides support for the use of hormone therapy for treatment of bothersome and distressing hot flashes, night sweats and other menopausal symptoms that may impair quality of life in women who don't have a reason not to take hormone therapy", said lead author Dr. JoAnn Manson. During the five to seven years of treatment, the death rates in the women aged 50-59 tended to be approximately 30 percent lower among women who received hormone therapy when compared to women of the same age who received placebo.

Hormone therapy is known to be effective in reducing hot flashes and menopausal symptoms, and decreasing the risk of hip and other fractures, but it has been also linked to risks including venous blood clots, stroke, and certain cancers.

By the end of the 18-year study, the death rates from any cause among the women receiving some form of hormone therapy were similar to that of women who took the placebo.

Among the youngest women, there were fewer overall deaths early on among hormone users than dummy-pill users, but the rates evened out after women stopped using the pills.

Liverpool to appeal Mane's red card ban
City then travel to Watford in the Premier League and Liverpool host Burnley , both games on Saturday, 16 September. When he saw the boy bleeding, if I was in that position I would probably have made the same decision.

The brands studied were Prempro estrogen-progestin pills and Premarin estrogen-only pills. Hormone therapy is no longer widely recommended to prevent chronic disease like osteoporosis, heart disease or cancer, as they previously were. "In this new analysis, we found that there was no association between hormone therapy and all-cause mortality during either the treatment period or the long-term follow-up of these trials", Manson said.

These latest results from the Women's Health Initiative (WHI) trials shed more nuanced light on findings published in 2002 from the same study, said Dr. Len Lichtenfeld, deputy chief medical officer for the American Cancer Society.

Women wanted to know "Is this medication going to kill me?" and the answer appeared to be no, she said. They found the treatment did not lead to early death from any cause.

Overall, nearly 7,500 women died, which was about 27 percent each in the hormone and dummy pill groups. The women took the hormone therapy for five to seven years. After that, many doctors became reluctant to prescribe hormone therapy for menopause symptoms.

"We found that hormone therapy really didn't affect most other types of cancer, so the overall effect of hormones on cancer deaths was neutral", Manson said.

More research is necessary on the long-term benefits and risks of newer hormone therapies, the researchers say.

Related news