Nobel Prize 2017: Cryo-Electron Microscopy Developers Trio Honoured With Chemistry Award

Nobel Prize 2017: Cryo-Electron Microscopy Developers Trio Honoured With Chemistry Award

Nobel Prize 2017: Cryo-Electron Microscopy Developers Trio Honoured With Chemistry Award

Jacques Dubochet, Joachim Frank and Richard Henderson have won the Nobel Prize for chemistry for their work to simplify and improve the imaging of biomolecules.

Henderson, a professor at the Molecular Research Council (MRC) Laboratory of Molecular Biology in the United Kingdom, produced the first high-resolution model of a protein, bacteriorhodopsin, using electron cryo-microscopy (cryo-EM) in 1990.

Today, three scientists have been awarded the Nobel Prize in chemistry for their work developing a new method to image biomolecules, including viruses like Zika, in incredibly high resolution.

Through this method, researchers can now "stop" biomolecules in motion and "to visualize the process, which they've never seen before".

Jacques Dubochet, Joachim Frank and Richard Henderson have won the 2017 Nobel Prize in chemistry for developing a way to image biomolecules at cold temperatures. In the past, electron microscopes were also assumed to be useful only in imaging dead material due to electron beams destroying biological matter.

"Normally what I'd do if I was in Cambridge, we will have a party around tea-time in the lab but I expect we'll have it tomorrow instead", said Henderson. "They've opened up a completely new world to us, to see these molecules in the cell and how they interact", Peter Brzezinski, a biochemist at Stockholm University, said at this morning's announcement in the Swedish capital.

In the 1970s Henderson, of the MRC Laboratory of Molecular Biology in Cambridge UK, and his colleague Nigel Unwin were trying to determine the shape of a protein called bacteriorhodopsin.

Premier League clubs split over overseas rights payments
Other activities at Premier League Live will include live screening of five EPL matches and local music acts and DJs. The fans are some of the most passionate around and I am really looking forward to meeting some of them on Saturday.

"To give one example, previous year the 3D structure of the enzyme producing the amyloid (protein) of Alzheimer's disease was published using this technology", Hardy said.

Dubochet added water to electron microscopy.

'Biochemical maps have always been filled with blank spaces because the available technology has had difficulty generating images of much of life's molecular machinery.

The scientists developed a way to generate three-dimensional images of molecules, which the academy said has brought biochemistry "into a new era".

Rainer Weiss, Kip Thorne and Barry Barish were awarded the Nobel Prize for Physics on Tuesday. Most other proteins, by contrast, are disorderly, asymmetrical and filled with randomly positioned particles.

The chemistry prize was the third Nobel announced this week. This year the prizes are worth 9 million kronor (1.1 million dollars).

Additional Nobel Prizes will be awarded over the next few days - literature on Thursday, peace on Friday and economics on October 9.

Related news