FDA's New Warning on Kratom: What Makes Something an Opioid?

FDA's New Warning on Kratom: What Makes Something an Opioid?

FDA's New Warning on Kratom: What Makes Something an Opioid?

Now, FDA commissioner Scott Gottlieb has gone a step further by releasing what the agency says is strong evidence that kratom compounds are themselves opioids.

The agency's conclusion is based on recent computational modelling and on scientific literature and reports of adverse effects in people, he said. The scientific data and adverse event reports have "clearly revealed" that compounds in kratom render it more unsafe than "just a plant", he said.

The FDA is warning individuals to avoid using kratom, which has been used by some as a remedy for opioid addiction and to treat addicts' medical conditions, as the herbal drug is "predicted to affect the body just like opioids" do.

"Today, we're providing details of some of the important scientific tools, data and research that have contributed to the FDA's concerns about kratom's potential for abuse, addiction, and serious health consequences; including death", Gottlieb said. He noted that, "Given all these considerations, we must ask ourselves whether the use of kratom-for recreation, pain, or other reasons-could expand the opioid epidemic". This technology was used to detect how the brain reacts when it is exposed to kratom.

In 2016, the Drug Enforcement Administration (DEA) announced plans to temporarily list kratom as a Schedule I controlled substance, which would put it in the same category as heroin. But officials backtracked after a public outcry and pressure from some members of Congress.

The FDA stands ready to evaluate evidence that could demonstrate a medicinal goal for kratom.

Drake $50k Gift Will Help Pay for Brand New Shelter!!!
The music producer also teamed up with Migos in the group's song "Deadz" and Kendrick Lamar for his track "GOD". After meeting James, Drake went on to donate $25,000 to Miami Senior High School.

The FDA provided that evaluation late past year.

The agency previously warned of kratom's side effects, including seizures and respiratory depression.

FDA scientists analyzed the 25 most common chemical compounds in kratom and concluded that they behave like those found in opioids including morphine. Using a computer model, FDA researchers found that most of the compounds in kratom bind to opioid receptors in the body.

After the FDA's November announcement, Jack Henningfield, an addiction specialist who works at the drug policy consulting group Pinney Associates, said that surveys of kratom users suggest that many are taking the supplement to help stop using opioids. Federal agencies must move quickly to assess the abuse potential of newly identified designer street drugs for which limited or no pharmacological data are yet available.

However, the American Kratom Association (AKA), a vocal advocate for the drug, calls the FDA's assessment "utterly and completely wrong", comparing it to a trick play to pressure the DEA into banning the substance.

Related news